Mimicking in vivo performance

Grow your cells using CelVivo’s 3D cell culture technology to generate in vitro models that closely resemble real-world conditions.

Highlighted ClinoStar publications

Blastoids mimic IVF-derived blastocysts when grown in a 3D environment.

See this breakthrough publication, which holds great potential to advance animal agriculture by providing an accessible in vitro blastoid model for studying bovine embryogenesis.

Omicron BA.5 infects human brain organoids

COVID-19 has affected human brain organoids. See this publication about how some BA.5 infected patients are experiencing increased loss of the sense of smell (anosmia).

Pushing the frontiers of in vitro models


In close collaboration with scientists, CelVivo aims to innovate 3D cell culture research, pushing the frontiers of in vitro models by solving the bias of active diffusion and no shear stress.

This means that cells can present a physiological performance similar to what is seen in vivo and the re-establishment of intercellular communication, whether they are spheroids, organoids, or other aggregates.


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Application Areas

The ClinoStar 3D cell culture technology is made for scientists who cultivate and mature cells.

The technology can be used across several application areas and allows the generation of uniform, reproducible, and functional spheroids and organoids. These spheroids mimic the function, structure, and architecture of in vivo cells. The technology thus lets you perform research using cell models with an unprecedented correlation between in vivo and in vitro conditions and closes the gap between 2D cell culture and cell function.

See how it works on the application areas below.

Developmental Biology

Read new publications about how blastoids grown in a 3D cell culture environment can create in vitro models of blastocysts.

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Watch exclusive webinars and interviews, and learn how other scientists work with long-term liver cell cultures in the ClinoStar system.

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See how other scientists have used the ClinoStar system for growing brain organoids in a 3D environment and how to get started yourself.

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Immersive yourself in insights about working with tumoroids in 3D and how other scientist uses the ClinoStar for oncological research.

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The CelVivo Technology

The ClinoStar technology is developed to mimic in vivo performance with low sheer stress, allowing scientists to generate in vitro models that closely resemble real-world conditions. Thus creating more accurate, reproducible research and experiments – without animal use.

How japan and South Korea are transforming 3D cell culture technology

ClinoStar Users



Start your journey with stress-free 3D today. Download our booklet to see all the details on how you create beautiful organoids and spheroids and learn more about the growing of constructs in an in vivo-like environment.


Cell Culture History


Cell culture involves isolating cells from an organism and providing conditions to keep them alive and proliferate. Initially, this was done by growing the cells on flat surfaces (2D). However, with the realization that 2D performance has limitations, the focus shifted towards growing cells as clusters (organoids or spheroids), where they more closely mimic what occurs in vivo.


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Do you need support with your ClinoStar? Do you have any questions regarding applications or protocols? Visit our support site to get answers to our frequently asked questions or contact a CelVivo employee.


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